(Pyridin-4-yl)boronic acid → HCID 71557601, compound

HRID 920909Notes

Reaction equation

HRID 920909 reaction equation
Br[C:2]1[C:10]2[C:9](=[O:11])[N:8]([CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[N:7]=[CH:6][C:5]=2[S:4][CH:3]=1.[N:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1>>[N:20]1[CH:25]=[CH:24][C:23]([C:2]2[C:10]3[C:9](=[O:11])[N:8]([CH2:12][CH2:13][C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=4)[N:7]=[CH:6][C:5]=3[S:4][CH:3]=2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 86683121HCID 86683121, compound

Product 1

HCID 71557601HCID 71557601, compoundYield 33.1%

Procedure

The title compound was prepared in analogy to the process described in Example 3.5 starting from 3-bromo-5-(2-pyridin-2-yl-ethyl)-5H-thieno[2,3-d]pyridazin-4-one and pyridine-4-ylboronic acid. Yield: 33.1%.

Sources & evidence

ORD record
ord-d2bd27a547d949ddb5480d78e483fb65
Source dataset
uspto-grants-2016_03
Patent number
US09273068B2

Reaction notes

Loading…