Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 921398Generated: October 30, 2026

4-(Dimethylphosphoryl)-2-ethylaniline → N2-[4-(dimethylphosphoryl)-2-ethylphenyl]-N4-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine-2,4-diamine

https://huagongshe.com/reaction/921398

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Dimethylphosphoryl)-2-ethylanilineHCID 67052679—
Reactant2-chloro-N-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridin-4-amineHCID 86668814—
ProductN2-[4-(dimethylphosphoryl)-2-ethylphenyl]-N4-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine-2,4-diamineHCID 68165246—

Reaction Steps

This compound can be prepared as described in Example 80 by reacting 2-chloro-N-[2-(propan-2-ylsulfonyl)phenyl]-5-(trifluoromethyl)pyridin-4-amine with 4-(Dimethylphosphoryl)-2-ethylaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273077B2
Source datasetuspto-grants-2016_03
ORD IDord-b24dc626d735474eacab4c403b3c965a
Source noteuspto-grants-2016_03