m-Chloroperbenzoic acid → HCID 178526242, 화합물

HRID 921518노트

반응식

HRID 921518 반응식
[F:1][C:2]([F:13])([F:12])[C:3]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][CH:10]=2)[NH:5][N:4]=1.ClC1C=C(C=CC=1)C(OO)=[O:19]>COCCOC.CCCCCCC>[F:13][C:2]([F:1])([F:12])[C:3]1[C:11]2[C:6](=[N+:7]([O-:19])[CH:8]=[CH:9][CH:10]=2)[NH:5][N:4]=1

참가 물질

5

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 178506292HCID 178506292, 화합물

생성물 1

HCID 178526242HCID 178526242, 화합물수율 96%

시약·촉매·용매 2

HCID 80711,2-Dimethoxyethane용매HCID 8900Heptane용매

실험 절차

Compound (1a) was dissolved in ethylene glycol dimethyl ether (100 mL) and heptane (200 mL), and m-chloroperoxybenzoic acid (33.9 g) was added to the resulting solution at 0° C., followed by stirring at room temperature for 1 hr. The precipitate was collected by filtration to obtain compound (1b) (33.3 g, 96%) as a white solid.

후처리

  1. filtrationThe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-dde36547ceba4181b6d78529ef682886
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09273045B2

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