Methanol → 1,1-Dimethylethyl 4-[(2-amino-5-cyclopropyl-3-fluorophenyl)amino]-1-piperidinecarboxylate
Reaction equation
[CH3:28][OH:29].[CH:1]1([c:4]2[cH:5][c:6]([F:27])[c:7]([N+:24]([O-:25])=[O:26])[c:8]([NH:10][CH:11]3[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]3)[cH:9]2)[CH2:2][CH2:3]1.[Pd:30]>>[CH:1]1([c:4]2[cH:5][c:6]([F:27])[c:7]([NH2:24])[c:8]([NH:10][CH:11]3[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]3)[cH:9]2)[CH2:2][CH2:3]1Participants
4
Sources & evidence
- ORD record
- ord-c6460d316ef34a13b9646d34c62840d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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