HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(4-Hydroxy-2-methoxyphenyl)propanoate → 3-[2-methoxy-4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(4-Hydroxy-2-methoxyphenyl)propanoate | HCID 66685654 | — |
| Reactant | (4-{[(2E)-2-(methoxyimino)-2-phenylethyl]oxy}phenyl)methanol | HCID 86695770 | — |
| Product | 3-[2-methoxy-4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]propanoic acid | HCID 56640143 | 89% |
Reaction Steps
Compound 37 was synthesized from (1Z)-2-[4-(hydroxymethyl)phenoxy]-1-phenylethanone O-methyloxime (0.4 g, 1.197 mmol) and methyl 3-(4-hydroxy-2-methoxyphenyl)propanoate (0.268 g, 1.197 mmol) by following the procedure described in scheme 13 (0.2 g, yield: 89%); Purity: 99.31%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278915B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-a6e75640756649a5a9ac2ccfb222e522 |
| Source note | uspto-grants-2016_03 |