Sodium Hydroxide → HCID 56640355, compound

HRID 922225Notes

Reaction equation

[OH-].[Na+:2].[C:3]([CH:5]([C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][CH2:27]/[C:28](=[N:35]/[O:36][CH3:37])/[C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:22][CH:21]=2)=[CH:14][CH:13]=1)[CH2:6][C:7]([O:9]CC)=[O:8])#[N:4]>>[C:3]([CH:5]([C:12]1[CH:13]=[CH:14][C:15]([O:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][CH2:27]/[C:28](=[N:35]/[O:36][CH3:37])/[C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)=[CH:22][CH:21]=2)=[CH:16][CH:17]=1)[CH2:6][C:7]([O-:9])=[O:8])#[N:4].[Na+:2]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 86695731HCID 86695731, compound

Product 1

HCID 56640355HCID 56640355, compoundYield 67.38%

Procedure

Compound 53 was synthesized from sodium hydroxide (0.05 g, 1.27 mmol) and ethyl 3-cyano-3-{4-[(4-{[(2E)-2-(methoxyimino)-2-phenylethyl]oxy}benzyl)oxy]phenyl}propanoate (0.3 g, 0.64 mmol) by following the procedure described in scheme 12 (0.2 g, yield: 67.38%); Purity: 89.99%.

Sources & evidence

ORD record: ord-7266dc5bd81d47919af25c0ccde26f79
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09278915B2

Reaction notes

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