Benzenepropanoic acid, 4-hydroxy-, methyl ester → HCID 56640646, compound

HRID 922284Notes

Reaction equation

HRID 922284 reaction equation
[CH3:1][O:2]/[N:3]=[C:4](/[C:15]1[CH:20]=[CH:19][C:18]([S:21]([CH3:24])(=[O:23])=[O:22])=[CH:17][CH:16]=1)\[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1.O[C:26]1[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][C:34]([O:36]C)=[O:35])=[CH:28][CH:27]=1>>[CH3:1][O:2]/[N:3]=[C:4](/[C:15]1[CH:20]=[CH:19][C:18]([S:21]([CH3:24])(=[O:23])=[O:22])=[CH:17][CH:16]=1)\[CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][O:14][C:26]2[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[CH:28][CH:27]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 79706Benzenepropanoic acid, 4-hydroxy-, methyl esterHCID 89790263HCID 89790263, compound

Product 1

HCID 56640646HCID 56640646, compoundYield 39.91%

Procedure

Compound 92 was synthesized from [4-({(2Z)-2-(methoxyimino)-2-[4-(methylsulfonyl)phenyl]ethyl}oxy)phenyl]methanol (0.57 g, 1.63 mmol) and methyl 3-(4-hydroxyphenyl)propanoate (0.293 g, 1.63 mmol) by following the procedure described in scheme 5 (0.2 g, yield: 39.91%); Purity: 96.52%.

Sources & evidence

ORD record
ord-eec5e59a1ab642f781eb40e0bccef50b
Source dataset
uspto-grants-2016_03
Patent number
US09278915B2

Reaction notes

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