Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 922285Generated: October 26, 2026

Ethyl 3-(4-hydroxy-3-methoxyphenyl)propionate → 3-[3-methoxy-4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]propanoic acid

https://huagongshe.com/reaction/922285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-(4-hydroxy-3-methoxyphenyl)propionateHCID 123548—
Reactant(4-{[(2E)-2-(methoxyimino)-2-phenylethyl]oxy}phenyl)methanolHCID 86695770—
Product3-[3-methoxy-4-[[4-[(2Z)-2-methoxyimino-2-phenylethoxy]phenyl]methoxy]phenyl]propanoic acidHCID 5664071147.62%

Reaction Steps

Compound 94 was synthesized from (4-{[(2Z)-2-(methoxyimino)-2-phenylethyl]oxy}phenyl)methanol (0.12 g, 0.446 mmol) and ethyl 3-(4-hydroxy-3-methoxyphenyl)propanoate (0.1 g, 0.446 mmol) by following the procedure described in scheme 16 (0.06 g, yield: 47.62%); Purity: 98.66%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278915B2
Source datasetuspto-grants-2016_03
ORD IDord-2d3144fb24834a70a712104ea7eb408a
Source noteuspto-grants-2016_03