Benzenepropanoic acid, 4-hydroxy-, methyl ester → HCID 56639704, compound

HRID 922293Notes

Reaction equation

HRID 922293 reaction equation
[CH3:1][O:2]/[N:3]=[C:4](/[C:15]1[S:16][C:17]2[C:24]([CH3:26])([CH3:25])[CH2:23][CH2:22][C:21]([CH3:28])([CH3:27])[C:18]=2[C:19]=1[CH3:20])\[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1.O[C:30]1[CH:35]=[CH:34][C:33]([CH2:36][CH2:37][C:38]([O:40]C)=[O:39])=[CH:32][CH:31]=1>>[CH3:1][O:2]/[N:3]=[C:4](/[C:15]1[S:16][C:17]2[C:24]([CH3:26])([CH3:25])[CH2:23][CH2:22][C:21]([CH3:28])([CH3:27])[C:18]=2[C:19]=1[CH3:20])\[CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][O:14][C:30]2[CH:35]=[CH:34][C:33]([CH2:36][CH2:37][C:38]([OH:40])=[O:39])=[CH:32][CH:31]=2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 79706Benzenepropanoic acid, 4-hydroxy-, methyl esterHCID 87106864HCID 87106864, compound

Product 1

HCID 56639704HCID 56639704, compoundYield 2.16%

Procedure

Compound 106 was synthesized from (4-{[(2E)-2-(methoxyimino)-2-(3,4,4,7,7-pentamethyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)ethyl]oxy}phenyl)methanol (0.3 g, 0.7 mmol) and methyl 3-(4-hydroxyphenyl)propanoate (0.135 g, 0.7 mmol) by following the procedure described in scheme 5 (0.008 g, yield: 2.16%); Purity: 97.59%.

Sources & evidence

ORD record
ord-ffe6b1a9d12f4394a9f88972b7c886f4
Source dataset
uspto-grants-2016_03
Patent number
US09278915B2

Reaction notes

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