Ethanol → HCID 87106032, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of ethyl (2E)-3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)prop-2-enoate (0.13 g, 0.3 mmol) in ethanol was added pyridine (0.038 g, 0.45 mmol) and O-Methoxylamine hydrochloride, the resulting mass was refluxed at 80° C. for 3 h. Reaction quenched with water and extracted with ethyl acetate, organic layer was washed with water and brine solution dried over anhydrous Na2SO4 and concentrated to colourless oil (0.03 g, Yield: 23%); MS (ESI, 120 eV): m/z=449 (M+H)+.

Provenance & Evidence