Cyclopropylamine → HCID 89925443, compound

HRID 922482Notes

Reaction equation

HRID 922482 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:9](=O)[CH3:10])[CH:5]=[N:6][C:7]=1[Cl:8].[CH:12]1([NH2:15])[CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:3]=[C:4]([CH:9]([NH:15][CH:12]2[CH2:14][CH2:13]2)[CH3:10])[CH:5]=[N:6][C:7]=1[Cl:8]

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 200719921-(5-Bromo-6-chloro-pyridin-3-yl)-ethanone

Product 1

HCID 89925443HCID 89925443, compound

Procedure

1-(5-Bromo-6-chloropyridin-3-yl)ethanone and cyclopropylamine were treated in the similar manner to Reference Example 6(6) to give N-[1-(5-bromo-6-chloropyridin-3-yl)ethyl]cyclopropylamine [REx(113-2)] as a pale yellow oil.

Sources & evidence

ORD record
ord-67320dca35f24f909166e5375c3d6d5f
Source dataset
uspto-grants-2016_03
Patent number
US09278944B2

Reaction notes

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