反应详情

温度

70 °C

To a mixture of 13.0 g (78.2 mmol) of 2-(4-hydroxyphenyl)propionic acid in 250 ml EtOH 5.82 ml (78.2 mmol) thionyl chloride are added slowly at 0° C. The reaction mixture is stirred at 70° C. for 2 h. After cooling to r.t. the solvent is removed in vacuo. The residue is mixed with toluene and the solvent is removed again.

1. additionare added slowly at 0° C
2. temperatureAfter cooling to r.t. the solvent
3. customis removed in vacuo
4. additionThe residue is mixed with toluene
5. customthe solvent is removed again