Water → HCID 12373571, compound

HRID 922566Notes

Reaction equation

HRID 922566 reaction equation
[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[O:6][C:5]=2[C:4]([CH:14]=[O:15])=[CH:3][CH:2]=1.[BH4-].[Na+].O>C(O)C>[CH:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[O:6][C:5]=2[C:4]([CH2:14][OH:15])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 962WaterHCID 1260434-DibenzofurancarboxaldehydeHCID 4311764Sodium borohydride

Product 1

HCID 12373571HCID 12373571, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1 g (5.1 mmol) of Dibenzofuran-4-carboxaldehyde is dissolved in 5 ml of ethanol. 0.24 g of NaBH4 is then added portionwise to the stirred solution during a period 20 minutes. The solution is maintained under stirring at room temperature for 2 hours, following which the solvent is evaporated. The residue obtained is treated with water, and aqueous layer is then extracted with ether. Evaporation of the organic phase yielded 0.90 g of Dibenzofuran-4-ylmethanol.

Workup

  1. temperatureThe solution is maintained
  2. customis evaporated
  3. customThe residue obtained
  4. extractionis then extracted with ether
  5. customEvaporation of the organic phase

Sources & evidence

ORD record
ord-d6d25294ec684983bd49a6e96e44511c
Source dataset
uspto-grants-2016_03
Patent number
US09278957B2

Reaction notes

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