2-Bromomethylnaphthalene → HCID 178478239, compound

Participants

Reaction Steps

1-(Benzo[1,4]dioxan-2-ylmethyl)-4,5-dichloroimidazole (0.28 g, 1 mmol) was combined with acetonitrile (2 mL) and heated until all solid dissolved. 2-(Bromomethyl)naphthalene (0.22 g, 1 mmol) was added and the solution was refluxed for 3 h, during which time a white precipitate formed. The precipitate was collected by filtration and washed with diethyl ether to yield a white solid (0.29 g, 57% yield). 1H NMR (300 MHz, DMSO-d6) 9.65 (1H, s, NCHN), 8.00 (4H, m, Ar), 7.57 (3H, m, Ar), 6.87 (4H, m, Ar), 5.72 (2H, s, CH2), 4.11-4.88 (5H, m, CH2CHCH2O).

Provenance & Evidence