反应详情

4,5-dichloroimidazole (1.00 g, 7.36 mmol) was dissolved in acetonitrile. Potassium hydroxide (0.828 g, 14.72 mmol) was added to the solution and allowed to reflux for 30 min. 2 equivalents of 2-bromopentanoic acid (2.66 g, 14.72 mmol) was added to the solution and refluxed for 5 h. Solution was filtered to remove the KBr precipitate and neutralized with 6M HBr. Volatiles were removed in vacuo and the resulting product will be collected and analyzed.

1. temperatureto reflux for 30 min
2. temperaturerefluxed for 5 h
3. filtrationSolution was filtered
4. customto remove the KBr precipitate
5. customVolatiles were removed in vacuo
6. customthe resulting product will be collected