HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → N1-tert-butyl-N4-(4-chloro-3-(pyridin-2-yl)phenyl)terephthalamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | 4-(4-Chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid | HCID 66877887 | — |
| Product | N1-tert-butyl-N4-(4-chloro-3-(pyridin-2-yl)phenyl)terephthalamide | HCID 58614838 | — |
Reaction Steps
50 mg of 4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to tert-butylamine via Procedure G. The product was purified on reverse phase HPLC to yield N1-tert-butyl-N4-(4-chloro-3-(pyridin-2-yl)phenyl)terephthalamide. MS (Q1) 408 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278961B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-fcd84a569fc6428186d1e80950c9b0ab |
| Source note | uspto-grants-2016_03 |