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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 922895Generated: October 31, 2026

1-(2-Hydroxyethyl)piperazine → HCID 58614659, compound

https://huagongshe.com/reaction/922895

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66878605—
ProductHCID 58614659HCID 58614659—

Reaction Steps

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to N-(2-hydroxyethyl)piperazine via Procedure G. The product was purified on reverse phase HPLC to yield 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)benzamide. MS (Q1) 499 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278961B2
Source datasetuspto-grants-2016_03
ORD IDord-708050c8dbac4d8db6cca8d27f9ca37b
Source noteuspto-grants-2016_03