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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 922906Generated: October 30, 2026

4,5-Dihydro-2-thiazolamine → HCID 58614922, compound

https://huagongshe.com/reaction/922906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,5-Dihydro-2-thiazolamineHCID 15689—
Reactant3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66878605—
ProductHCID 58614922HCID 58614922—

Reaction Steps

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to 2-amino-4,5-dihydrothiazole via Procedure G. The product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(4,5-dihydrothiazol-2-yl)terephthalamide. MS (Q1) 471 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278961B2
Source datasetuspto-grants-2016_03
ORD IDord-f7692e1084c747328965b9710da5f182
Source noteuspto-grants-2016_03