HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-(+)-cis-1-Amino-2-indanol → HCID 58614946, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
| Reactant | 3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid | HCID 66878605 | — |
| Product | HCID 58614946 | HCID 58614946 | — |
Reaction Steps
60 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to (1R,2S)-1-amino-2,3-dihydro-1H-inden-2-ol via Procedure G. The crude product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)terephthalamide. MS (Q1) 518.2 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278961B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-bdc2fc6403004bbc96e7e25ba1b7edb3 |
| Source note | uspto-grants-2016_03 |