HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methylhomopiperazine → N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(4-methyl-1,4-diazepan-1-yl)nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methylhomopiperazine | HCID 228349 | — |
| Edukt | 6-Chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]pyridine-3-carboxamide | HCID 58614810 | — |
| Produkt | N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(4-methyl-1,4-diazepan-1-yl)nicotinamide | HCID 58614623 | — |
Reaktionsschritte
50 mg of 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)nicotinamide was reacted with 1-methyl-1,4-diazepane via Procedure F. The reaction was evaporated to dryness and purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-6-(4-methyl-1,4-diazepan-1-yl)nicotinamide. MS (Q1) 422 (M)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09278961B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-8df0840624f443c9bc635ea2832e0cf2 |
| Quellennotiz | uspto-grants-2016_03 |