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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 923038Generated: October 30, 2026

2,6-Dimethylpiperazine → HCID 58614849, compound

https://huagongshe.com/reaction/923038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-DimethylpiperazineHCID 66056—
Reactant4-(Chlorosulfonyl)benzoic acidHCID 82385—
Reactant4-Chloro-3-(pyridin-2-yl)anilineHCID 40151925—
ReactantHCID 66878121HCID 66878121—
ProductHCID 58614849HCID 58614849—

Reaction Steps

1 g of 4-(chlorosulfonyl)benzoic acid was reacted with 570 mg of 2,6-dimethylpiperazine via Procedure H. 75 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 119 mg of 4-(3,5-dimethylpiperazin-1-ylsulfonyl)benzoic acid via Procedure G and purified by reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(3,5-dimethylpiperazin-1-ylsulfonyl)benzamide. MS (Q1) 485.4 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278961B2
Source datasetuspto-grants-2016_03
ORD IDord-1a1e66e857d6402f93c88eb7d930c1a1
Source noteuspto-grants-2016_03