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HRID923137

反应详情

EQUATION

反应方程式

HRID 923137 的结构方程式

REACTANTS

反应物

2
结构：O=C1CNCCN1
HCID231360

Piperazin-2-one

C4H8N2O

结构：Cc1nc(Cl)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1
HCID58614798

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(N2CCNC(=O)C2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1
HCID58614776

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCO
溶剂HCID263

1-Butanol

C4H10O

PROCEDURE

实验过程

Procedure F was performed using 100 mg of 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methylnicotinamide and 84 mg of piperazine-2-one in 1 mL of BuOH. Purified by reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(3-oxopiperazin-1-yl)nicotinamide. MS (Q1) 422.3 (M)+.

WORKUP

后处理

  1. customPurified by reverse phase HPLC