HCID 66736169, compound → HCID 24826716, compound

HRID 923213Notes

Reaction equation

HRID 923213 reaction equation
[C:1]([C:3]1[N:7]2[CH:8]=[CH:9][CH:10]=[C:11]([NH:12][C:13]3[CH:18]=[CH:17][C:16]([S:19](=[O:22])(=[O:21])[NH2:20])=[CH:15][CH:14]=3)[C:6]2=[N:5][CH:4]=1)#[CH:2].I[C:24]1[CH:25]=[C:26]([CH:40]=[CH:41][C:42]=1[CH3:43])[C:27]([NH:29][C:30]1[CH:35]=[C:34]([C:36]([F:39])([F:38])[F:37])[CH:33]=[CH:32][N:31]=1)=[O:28]>>[CH3:43][C:42]1[CH:24]=[CH:25][C:26]([C:27]([NH:29][C:30]2[CH:35]=[C:34]([C:36]([F:37])([F:38])[F:39])[CH:33]=[CH:32][N:31]=2)=[O:28])=[CH:40][C:41]=1[C:2]#[C:1][C:3]1[N:7]2[CH:8]=[CH:9][CH:10]=[C:11]([NH:12][C:13]3[CH:14]=[CH:15][C:16]([S:19](=[O:21])(=[O:22])[NH2:20])=[CH:17][CH:18]=3)[C:6]2=[N:5][CH:4]=1

Participants

3

Reactant 2

HCID 66736169HCID 66736169, compoundHCID 86614282HCID 86614282, compound

Product 1

HCID 24826716HCID 24826716, compound

Procedure

The title compound was synthesized from 3-ethynyl-N-(4-sulfamoylphenyl)imidazo[1,2-a]pyridin-8-amine and 3-iodo-4-methyl-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide in a manner similar to that described for Example 12. The product was obtained as a solid: 591 m/z (M+H).

Workup

  1. customThe product was obtained as a solid

Sources & evidence

ORD record
ord-8f33d9ed36f54a939ef3bf9cdc12e476
Source dataset
uspto-grants-2016_03
Patent number
US09278971B2

Reaction notes

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