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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 92324Generated: October 25, 2026

Chloride → Tert-butyl 2-(2,5-difluorophenyl)-2-hydroxypyrrolidine-1-carboxylate

https://huagongshe.com/reaction/92324

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantMagnesium CationHCID 888—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant1-Pyrrolidinecarboxylic acid, 2-oxo-, 1,1-dimethylethyl esterHCID 379000—
ReactantHCID 178505814HCID 178505814—
ProductTert-butyl 2-(2,5-difluorophenyl)-2-hydroxypyrrolidine-1-carboxylateHCID 58335834—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-a13903fd12fb44af85fd6e9aae11d7ac
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)