HCID 178513167, compound → HCID 178508279, compound

HRID 923350Notes

Reaction equation

HRID 923350 reaction equation
[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][NH:7][C:8](=[NH:10])[NH2:9])=O>O>[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]1[N:9]=[C:8]([NH2:10])[NH:7][N:6]=1

Participants

3

Reactant 1

HCID 178513167HCID 178513167, compound

Product 1

HCID 178508279HCID 178508279, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2-(2-chlorobenzoyl)hydrazinecarboximidamide (3 g, 14.1 mmol) in water (10 mL) was stirred for 4 h at 100° C. After the reaction was completed, the solids were collected by filtration, and washed with H2O (3×5 ml). This resulted in 1.5 g (55%) of 3-(2-chlorophenyl)-1H-1,2,4-triazol-5-amine as a yellow oil.

Workup

  1. filtrationthe solids were collected by filtration
  2. washwashed with H2O (3×5 ml)
  3. customThis resulted in 1.5 g (55%) of 3-(2-chlorophenyl)-1H-1,2,4-triazol-5-amine as a yellow oil

Sources & evidence

ORD record
ord-0e3262359a624cd3aea333f5b44505bd
Source dataset
uspto-grants-2016_03
Patent number
US09278973B2

Reaction notes

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