2-Methoxyethylamine → HCID 59540249, compound

Participants

Reaction Steps

To a solution of 2-methoxyethylamine (0.343 mL, 3.99 mmol) in DMF (20.0 mL) at room temperature was added potassium carbonate (0.964 mL, 15.98 mmol) followed by 4-nitrobenzyl bromide (1.812 g, 8.39 mmol). The reaction was stirred for 2 hours then quenched with water, extracted with EtOAc and concentrated. The residue was purified by chromatography (20% to 40% EtOAc-hexane) to provide the title compound. MS (DCI) m/z 346 (M+H)+.

Provenance & Evidence