4-Nitrobenzyl bromide → HCID 59540364, compound

HRID 923409Notes

Reaction equation

HRID 923409 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[F:9])[NH2:5].[N+:10]([C:13]1[CH:20]=[CH:19][C:16]([CH2:17]Br)=[CH:15][CH:14]=1)([O-:12])=[O:11]>>[F:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[F:9])[N:5]([CH2:17][C:16]1[CH:19]=[CH:20][C:13]([N+:10]([O-:12])=[O:11])=[CH:14][CH:15]=1)[CH2:17][C:16]1[CH:19]=[CH:20][C:13]([N+:10]([O-:12])=[O:11])=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 660114-Nitrobenzyl bromideHCID 774693,4-Difluoroaniline

Product 1

HCID 59540364HCID 59540364, compound

Procedure

3,4-Difluoroaniline and 4-nitrobenzyl bromide were processed using the method described in Example 32A to afford the title compound. LC/MS Rt 2.15 m/z 400 (M+H)+.

Sources & evidence

ORD record
ord-bc0ee4b9821645d491fe7723541e59ae
Source dataset
uspto-grants-2016_03
Patent number
US09278922B2

Reaction notes

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