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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 923427Generated: November 2, 2026

HCID 14514526, compound → (2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid

https://huagongshe.com/reaction/923427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 14514526HCID 14514526—
CatalystHCID 178502593HCID 178502593—
SolventMethanolHCID 887—
Product(2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acidHCID 15622962102.8%

Reaction Steps

To a solution of the product from Example 123A (0.56 g, 1.6 mmol) in MeOH (8.0 mL) was added Pd(OH)2/carbon. The mixture was evacuated and a H2 atmosphere was introduced via a balloon. The mixture was stirred overnight then filtered and the solvent was removed under reduced pressure to provide the title compound (0.42 g, 102% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278922B2
Source datasetuspto-grants-2016_03
ORD IDord-9dc87f1063f2473eb6ade5c814c79c82
Source noteuspto-grants-2016_03