HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14514526, compound → (2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14514526 | HCID 14514526 | — |
| Catalyst | HCID 178502593 | HCID 178502593 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid | HCID 15622962 | 102.8% |
Reaction Steps
To a solution of the product from Example 123A (0.56 g, 1.6 mmol) in MeOH (8.0 mL) was added Pd(OH)2/carbon. The mixture was evacuated and a H2 atmosphere was introduced via a balloon. The mixture was stirred overnight then filtered and the solvent was removed under reduced pressure to provide the title compound (0.42 g, 102% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278922B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9dc87f1063f2473eb6ade5c814c79c82 |
| Source note | uspto-grants-2016_03 |