HCID 118318152, compound → HCID 118318071, compound

Participants

Reaction Steps

A mixture of 166 mg of tert-butyl [(1R)-2-(benzyloxy)-1-(2-methyl-2H-tetrazol-5-yl)ethyl]carbamate, 40 mg of 10% palladium-carbon (hydrous), and 8 ml of ethanol was stirred at room temperature for 18 hours under a hydrogen atmosphere of 4 atm. The reaction mixture was filtered over Celite and the filtrate was concentrated under reduced pressure to obtain 106 mg of tert-butyl [(1R)-2-hydroxy-1-(2-methyl-2H-tetrazol-5-yl)ethyl]carbamate.

Provenance & Evidence