反应详情

Under an argon atmosphere, to a solution of 400 mg of benzyl [2,2-dimethyl-5-(prop-2-yn-1-ylcarbamoyl)-1,3-dioxan-5-yl]carbamate in 4 ml of dichloromethane was added 104 mg of gold (III) chloride, followed by stirring at room temperature for 3 days. The reaction mixture was concentrated under reduced pressure and the obtained residue was purified by silica gel column chromatography to obtain 35 mg of benzyl [2,2-dimethyl-5-(5-methyl-1,3-oxazol-2-yl)-1,3-dioxan-5-yl]carbamate.

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customthe obtained residue was purified by silica gel column chromatography