Methyl N-(triethylammoniosulfonyl)carbamate → HCID 118308725, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 320 mg of tert-butyl 4-[(2-acetylhydrazino)carbonyl]-2,2,4-trimethyl-1,3-oxazolidine-3-carboxylate in 10 ml of dichloroethane was added 358 mg of a Burgess reagent ((methoxycarbonylsulfamoyl)triethylammonium hydroxide inner salt), followed by stirring at 80° C. for 2 hours. The reaction mixture was concentrated under reduced pressure and the obtained residue was purified by silica gel column chromatography to obtain 84 mg of tert-butyl 2,2,4-trimethyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)-1,3-oxazolidine-3-carboxylate.

Provenance & Evidence