2-Chloro-4,6-dimethyl-3-pyridinecarbonitrile → HCID 178425247, compound

HRID 923632Notes

Reaction equation

HRID 923632 reaction equation
Cl[C:2]1[N:9]=[C:8]([CH3:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].Cl[C:12]1[N:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[C:13]=1[C:14]#[N:15].NC(N)=[S:24]>>[SH:24][C:2]1[N:9]=[C:8]([CH3:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[SH:24][C:12]1[N:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[C:13]=1[C:14]#[N:15]

Participants

5

Reactant 3

HCID 2232612-Chloro-4,6-dimethyl-3-pyridinecarbonitrileHCID 5204002-Chloro-6-methylpyridine-3-carbonitrileHCID 2723790Thiourea

Product 2

HCID 178425247HCID 178425247, compoundHCID 178425618HCID 178425618, compound

Procedure

treating 2-chloro-6-methylnicotinonitrile (or 2-chloro-4,6-dimethylnicotinonitrile) with thiourea to give intermediate compound of 2-mercapto-6-methylnicotinonitrile (or 2-mercapto-4,6-dimethylnicotinonitrile);

Sources & evidence

ORD record
ord-a94d013f02b0425685272c2db0582ce3
Source dataset
uspto-grants-2016_03
Patent number
US09278982B2

Reaction notes

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