反应详情

温度

8 °C

Step 1: 1 Liter of ethanol was charged into a reactor and stirred rapidly. 0.3 kg of 6-chloroadenosine and 0.267 kg of cyclopentylamine were added to the ethanol in the reactor. The reactor was heated to reflux for 2 hr, then cooled to 8 degrees C. and kept under these conditions for 12 hours. The crystallized material was filtered from the mother liquid and the solid cake was washed with 0.33 L of ethanol to produced a wet cake. The wet cake was dried to obtain N6-cyclopentyladenosine (0.249 kg).

1. temperatureThe reactor was heated
2. temperatureto reflux for 2 hr
3. filtrationThe crystallized material was filtered from the mother liquid
4. washthe solid cake was washed with 0.33 L of ethanol
5. customto produced a wet cake
6. customThe wet cake was dried