HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromoanisole → HCID 90091086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromoanisole | HCID 7730 | — |
| Reactant | 1-Bromo-2,6-difluorobenzene | HCID 123557 | — |
| Reactant | (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate | HCID 11806530 | — |
| Reactant | N~2~-(tert-Butoxycarbonyl)-N-methoxy-N-methyl-D-alaninamide | HCID 23537239 | — |
| Product | HCID 90091086 | HCID 90091086 | — |
Reaction Steps
With the exception that (S)-t-butyl(1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate and 1-bromo-2,6-difluorobenzene were used instead of (R)-t-butyl(1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate and 4-methoxybromobenzene, respectively, the same procedure as in Preparation Example 5-5 was repeated to afford the title compound. 0.26 g (17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278996B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-ae5d821002584d40b828c4e3fdf134e8 |
| Source note | uspto-grants-2016_03 |