Triethylamine → HCID 90091394, compound

Participants

Reaction Steps

In a reaction vessel that was vacuumed and then purged with argon, (R)-t-butyl[1-phenyl-1-oxopropan-2-yl]carbamate (0.75 g (3.0 mmol)) and ammonium chloride (0.24 g (4.5 mmol)) were placed. Then, dry tetrahydrofuran (15 mL) and triethylamine (0.63 mL (4.5 mmol)) was added to the reaction vessel, followed by titanium tetraisopropoxide (1.32 mL (4.5 mmol)). At room temperature, the reaction mixture was stirred for 8˜10 hrs. After addition of ammonium borane, the reaction mixture was again stirred for 8˜10 hrs.

Provenance & Evidence