HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butyl 4-(3-(Tert-Butyldisulfanyl)-2-(Isobutoxycarbonylamino)Propanamido)Piperidine-1-Carboxylate → Isobutyl 3-(Isopropyldisulfanyl)-1-Oxo-1-(Piperidin-4-ylamino)Propan-2-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butyl 4-(3-(Tert-Butyldisulfanyl)-2-(Isobutoxycarbonylamino)Propanamido)Piperidine-1-Carboxylate | HCID 87107224 | — |
| Solvent | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Product | Isobutyl 3-(Isopropyldisulfanyl)-1-Oxo-1-(Piperidin-4-ylamino)Propan-2-ylcarbamate | HCID 71572473 | — |
Reaction Steps
To the compound from Example 60 (7.085 g, 18.12 mmol) was added 30 ml of 4M HCl/Dioxane. The reaction was completed after 2 h at RT. The title compound was used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09278987B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-e0ebc348c9da440287db5030fd9bbb32 |
| Source note | uspto-grants-2016_03 |