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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 923920Generated: October 30, 2026

(3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidine → HCID 118198935, compound

https://huagongshe.com/reaction/923920

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidineHCID 1514396—
Reactant5-bromo-6-chloro-N-(4-(trifluoromethoxy)phenyl)nicotinamideHCID 86702595—
ProductHCID 118198935HCID 118198935—

Reaction Steps

The title compound was prepared in an analogous fashion to that described in Stage 93.1 using 5-bromo-6-chloro-N-(4-(trifluoromethoxy)phenyl)nicotinamide (Stage 12.2) and (S)-tert-butyl pyrrolidin-3-ylcarbamate. LC-MS (Condition 6) tR=1.46 min, m/z=488.9 [M+H—H2C═C(CH3)2], m/z=544.9 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278981B2
Source datasetuspto-grants-2016_03
ORD IDord-c867010a6c854ebca73d182108741644
Source noteuspto-grants-2016_03