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HRID923940

反应详情

EQUATION

反应方程式

HRID 923940 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(O)C1CCNC1
HCID13900166

未命名化合物

结构：O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1
HCID86702595

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(O)C1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2Br)C1
HCID89907811

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described in Stage 33.1 using 5-bromo-6-chloro-N-(4-(trifluoromethoxy)phenyl)nicotinamide (Stage 12.2) and 3-(1-hydroxy-1-methyl-ethyl)-pyrrolidine (US2010160280) and was obtained as an off-white solid. HPLC (Condition 4) tR=6.11 min, UPLC-MS (Condition 7) m/z=490.1 [M+H]+.

WORKUP

后处理

  1. customwas obtained as an off-white solid