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HRID924029

反应详情

EQUATION

反应方程式

HRID 924029 的结构方程式

REACTANTS

反应物

2
结构：CNCCO
HCID8016

N-Methyl-N-hydroxyethylamine

C3H9NO

结构：O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(Br)c1
HCID72546089

未命名化合物

PRODUCTS

生成物

1
结构：CN(CCO)c1ncc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)cc1Br
HCID89906702

5-bromo-N-(4-(chlorodifluoromethoxy)phenyl)-6-((2-hydroxyethyl)(methyl)amino)nicotinamide

C16H15BrClF2N3O3

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described in Stage 33.1 using 5-bromo-6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)nicotinamide (Stage 169.2) and 2-methylamino-ethanol to afford as a white crystalline solid. HPLC (Condition 4) tR=5.72 min, UPLC-MS (Condition 3) tR=1.14 min, m/z=452.2 [M+H]+.

WORKUP

后处理

  1. customto afford as a white crystalline solid