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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 924065Generated: October 30, 2026

(R)-3-Pyrrolidinol → HCID 89906284, compound

https://huagongshe.com/reaction/924065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-PyrrolidinolHCID 2759337—
ReactantHCID 89906427HCID 89906427—
ProductHCID 89906284HCID 89906284—

Reaction Steps

The title compound was prepared in an analogous fashion to that described in Stage 33.1 using 5-bromo-6-chloro-N-(3-chloro-4-(trifluoromethoxy)phenyl)nicotinamide (Stage 204.2) and (R)-pyrrolidin-3-ol to afford an off-white crystalline solid. HPLC (Condition 4) tR=6.05 min, UPLC-MS (Condition 3) tR=1.24 min, m/z=480.1/482.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278981B2
Source datasetuspto-grants-2016_03
ORD IDord-bb77b62ee2554a338ae3372940d7f48c
Source noteuspto-grants-2016_03