反应详情

The title compound was prepared in an analogous fashion to that described in Stage 247.1 using 6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-5-iodonicotinamide (Stage 247.2) and 3-Fluoropyridine-5-boronic acid pinacolester (80° C. instead of 90° C.) to afford a white solid. UPLC-MS (Condition 3) tR=1.17 min, m/z=428.0/429.9 [M+H]+.

1. custom80° C.
2. custominstead of 90° C.
3. customto afford a white solid