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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 924189Generated: November 2, 2026

1-(2-Isopropyl-5-methylphenyl)thiourea → (1Z)-1-[3-(5-methyl-2-propan-2-ylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-3-[2-[4-[1-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]phenyl]ethyl]urea

https://huagongshe.com/reaction/924189

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Isopropyl-5-methylphenyl)thioureaHCID 89373168—
Reactant3-(4-(1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)propanoyl azide 3-(4-(2-isocyanatoethyl)phenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazoleHCID 131732837—
Product(1Z)-1-[3-(5-methyl-2-propan-2-ylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-3-[2-[4-[1-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]phenyl]ethyl]ureaHCID 90405254—

Reaction Steps

The title compound was prepared as described in Example 35 using 3-(4-(1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)propanoyl azide/3-(4-(2-isocyanatoethyl)phenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazole (C35b) and 1-(2-isopropyl-5-methylphenyl)thiourea and isolated as a tan glassy foam (0.132 g, 46%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09278964B2
Source datasetuspto-grants-2016_03
ORD IDord-82bb8be1e95e401ea1e19dac2ec4b960
Source noteuspto-grants-2016_03