HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Aluminum(III) Chloride → Methyl 2-fluoro-4-formyl-6-hydroxybenzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Aluminum(III) Chloride | HCID 6451240 | — |
| Edukt | Methyl 4-formyl-2-hydroxybenzoate | HCID 21626741 | — |
| Edukt | Methyl 2-fluoro-4-formyl-6-methoxybenzoate | HCID 86681499 | — |
| Produkt | Methyl 2-fluoro-4-formyl-6-hydroxybenzoate | HCID 86669343 | 97,1% |
Reaktionsschritte
Followed procedure described in Intermediate 5, step 3 starting with methyl 2-fluoro-4-formyl-6-methoxybenzoate (280 mg, 1.3 mmol) and AlCl3 (350 mg, 2.6 mmol) where reaction was complete after refluxing 10 min. Isolated 250 mg of Intermediate 7, yield 96%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09283213B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-9ff96bb5148345a9b04896f7a1f23f18 |
| Quellennotiz | uspto-grants-2016_03 |