Sodium Hydroxide → (3-Hydroxy-4-propionyl-2,6-dipropyl-phenoxy)-phenyl-acetic acid

HRID 9249Notes

Reaction equation

HRID 9249 reaction equation
[OH:1][C:2]1[C:3]([CH2:27][CH2:28][CH3:29])=[C:4]([C:17]([CH2:24][CH2:25][CH3:26])=[CH:18][C:19]=1[C:20](=[O:23])[CH2:21][CH3:22])[O:5][CH:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([O:9]C)=[O:8].[OH-].[Na+]>>[OH:1][C:2]1[C:3]([CH2:27][CH2:28][CH3:29])=[C:4]([C:17]([CH2:24][CH2:25][CH3:26])=[CH:18][C:19]=1[C:20](=[O:23])[CH2:21][CH3:22])[O:5][CH:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 21985968Methyl alpha-[3-hydroxy4-(1-oxopropyl)-2,6-dipropylphenoxy]benzeneacetate

Product 1

HCID 21985914(3-Hydroxy-4-propionyl-2,6-dipropyl-phenoxy)-phenyl-acetic acid

Procedure

The ester of step 2 (18.6 gm) was hydrolyzed with NaOH (98 ml) as for example 1, step 5.

Sources & evidence

ORD record
ord-9c83a6e508cf40888e8a12369cb3ade0
Source dataset
uspto-grants-2006_08
Patent number
US07091230B2

Reaction notes

Loading…