HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1,1'-Biphenyl)-4-yl-2-phenylethan-1-one → 1-[4-(Morpholin-4-yl)phenyl]-2-phenylethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1,1'-Biphenyl)-4-yl-2-phenylethan-1-one | HCID 74817 | — |
| Reactant | 4-(4-Bromophenyl)morpholine | HCID 11622851 | — |
| Product | 1-[4-(Morpholin-4-yl)phenyl]-2-phenylethanone | HCID 269696 | 36% |
Reaction Steps
Prepared from 4-(4-bromophenyl)morpholine following the procedure described in Intermediate 14, where the crude product was purified by column chromatography (PE:EtOAc=5:1) to afford Intermediate 25 (280 mg, yield 36%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09283229B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-e8c91a5ad1eb4b5f99dae0381382daeb |
| Source note | uspto-grants-2016_03 |