3-Fluoro-4-hydroxybenzaldehyde → HCID 18452164, compound

HRID 924982Notes

Reaction equation

HRID 924982 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=[O:6].[F:14]C1C=C(C=CC=1O)C=O>>[F:14][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 5872503-Fluoro-4-hydroxybenzaldehydeHCID 18452163HCID 18452163, compound

Product 1

HCID 18452164HCID 18452164, compoundYield 53%

Procedure

Followed procedure described for Intermediate 59, starting with 3-fluoro-4-hydroxybenzaldehyde. Desired product isolated in 53% yield.

Sources & evidence

ORD record
ord-e507ed4efb4d4dd2b461dae23b15904c
Source dataset
uspto-grants-2016_03
Patent number
US09283229B2

Reaction notes

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