HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 924991Generated: October 27, 2026
Ethyl Acetate → 4-Formyl-2-nitrobenzoic acid
https://huagongshe.com/reaction/924991
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4-Formyl-2-nitrobenzonitrile | HCID 22117815 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 4-Formyl-2-nitrobenzoic acid | HCID 20351439 | — |
Reaction Steps
A mixture of 4-formyl-2-nitrobenzonitrile (150 mg, 0.85 mmol) in conc. sulfuric acid (2 mL) and water (4 mL) was heated at 100° C. for 13 hours. Followed standard aqueous/EtOAc workup to give Intermediate 73.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09283229B2 |
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| Source dataset | uspto-grants-2016_03 |
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| ORD ID | ord-4bf4b1b81b4c4c0f8f73d76dd3cf44ac |
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| Source note | uspto-grants-2016_03 |
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