反应详情

Procedure as described for NP Amidine I using the following amounts: 1.19 g of N1-(2-ethylphenyl)-4-methylbenzamidine (Amidine VIII, 5.0 mmol), 2.50 mL of 2.0 M butyllithium (5.0 mmol), 0.93 mL chlorodiphenylphosphine (5.0 mmol). After filtration to remove lithium chloride and removal of solvent, the residue was treated with 20 mL of pentane. The light yellow solid was collected and dried (1.45 g, 69%).

1. filtrationAfter filtration
2. customto remove
3. customlithium chloride and removal of solvent
4. additionthe residue was treated with 20 mL of pentane
5. customThe light yellow solid was collected
6. customdried (1.45 g, 69%)