HCID 86725310, compound → HCID 76684261, compound

Participants

Reaction Steps

Example 10 was prepared in a similar fashion to Example 4, except Intermediate 4 was used as the starting material and phenylmagnesium bromide (3M in diethyl ether) was used instead of cyclopropylmagnesium bromide (Example 4, step (a)). NMR (300 MHz, CDCl3) δ 7.26-7.21 (m, 2H); 7.19-7.13 (m, 1H); 7.01 (s, 1H); 6.99-6.96 (m, 2H); 4.51-4.47 (m, 1H); 3.07-2.82 (m, 6H); 2.69-2.53 (m, 4H); 2.47-2.42 (m, 1H); 2.24-2.17 (m, 1H); 2.08-2.05 (m, 1H); MS: ESI (positive): 298, (M+1).

Provenance & Evidence