HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 3-(2-azidoethyl)-6-chloro-5-methyl-2-(triethylsilyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 3-(2-bromoethyl)-6-chloro-5-methyl-2-(triethylsilyl)-1H-indole | HCID 66831896 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(2-azidoethyl)-6-chloro-5-methyl-2-(triethylsilyl)-1H-indole | HCID 86663837 | — |
Reaction Steps
3-(2-azidoethyl)-6-chloro-5-methyl-2-(triethylsilyl)-1H-indole was prepared according to method D Step IV with 3-(2-bromoethyl)-6-chloro-5-methyl-2-(triethylsilyl)-1H-indole (0.725 g; 1.87 mmol) and sodium azide (0.365 g; 5.62 mmol) in DMF (8 mL); the yield was quantitative as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284271B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-4f5e77ec10e847bcb6f8bb6384c0ffd1 |
| Source note | uspto-grants-2016_03 |